TDF/SRY Disorder
Often called Testicular Feminization Syndrome, TDF/SRY is a disorder found in a person who has XY chromosomes (normal male), but is resistant to male hormones. As a result, the individual has some or all of the physical characteristics of a female. The syndrome is caused by various genetic mutations on the Y chromosome, making a developing male baby unable to respond to androgens (“Testicular Feminization” 1), which are hormones that promote male body characteristics (Shontz 525). Therefore, the development of the penis and other male body parts is restricted, and the child is born with the appearance of a girl. This occurs in as many as one in twenty thousand births (“Testicular Feminization” 1). Individuals with Testicular Feminization, or TDF/SRY, appear to be female externally, but typically do not have a uterus, cervix, or ovaries,
Complete TDF/SRY is rarely discovered during childhood, unless a mass is felt in the abdomen or groin, which turns out to be a testicle. Most with this condition are not diagnosed until they fail to menstruate or attempt pregnancy, but never conceive (“Testicular Feminization” 1). There are a few complications that can result if not treated properly, but life expectancy for people with testicular feminization is typically normal. Testicular tissue found within the abdomen or inguinal canal should be removed when puberty is complete because testicular cancers can develop within this tissue like any undescended testicle. Other cancers are common among those with abnormalities of sexual differentiation as well. Gender assignment is a very complex issue for those with testicular feminization, and psychosocial treatment is a large part of overcoming
Some topics in this essay:
Complete TDF/SRY,
Feminization TDF/SRY,
Syndrome TDF/SRY,
“testicular feminization”,
“testicular feminization” 1,
feminization” 1,
testicular feminization,
genetically male,
sry gene,
male babies,
genetically male babies,
,
Testicular Feminization,
abdomen inguinal canal,
male babies exhibit,
gender assignment,
“testicular feminization” 2,
physical characteristics,
inguinal canal,
feminization” 2,
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Approximate Word count = 577
Approximate Pages = 2 (250 words per page double spaced)
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