In this story, “Of Mice and Men” by John Steinbeck, George and Lennie travel all over the place together. They meet many people and go through many struggles together. I think that the theme of this story has to deal with loneliness and isolation. Many characters mention that they are unhappy or lonely. This story teaches a great lesson about the nature of human existence. “ ’Course Lennie’s a God damn nuisance most of the time,” said George. “But you get used to goin’ around with a guy an’ you can’t get rid of him.” This quote is said when George and Slim are talking in the b