A migraine is a neurovascular disorder which is said to be one of the world’s most disabling medical illnesses. A migraine occurs when Carla Bruegel, a stereotactic radiosurgery nurse at the Thomas Jefferson Hospital in Philadelphia, reports that in the United States, over 28 million adults suffer from migraines. In this article Bruegel seeks to answer what triggers a migraine, the different phases of a migraine and identifies and analyzes treatments that are available to patients with different levels of severity and migraine types.