Hypercholesterolemia
Hypercholesterolemia is a condition in which greater than normal amounts of cholesterol are present in the blood. High levels of cholesterol and other lipids may lead to the development of atherosclerosis. Hypercholesterolemia may be reduced or prevented by avoiding saturated fats, which are found in red meats, eggs, and dairy products, or certain medications. Hypercholesterolemia is sometimes inherited; in such cases diet is a less effective factor. Lipids are insoluble in water but soluble in alcohol, schoroform, ether, and other solvents. They are stored in the body and serve as an energy reserve, but are elevated in various diseases such as atherosclerosis. The kinds of lipids are cholesterol, fatty acids, neutral fat, phospholipids, and triglycerides. The normal concentrations of total lipids in serum are 400 to 800 mg/dl; cholesterol, 150 to 250 mg/dl; fatty acids, 9 to 15 mM/L; neutral fat, 0 to 200 mg/dl; phospholipids, 150 to 380 mg/dl; triglycerides, 10 to 190 mg/dl. There is good cholesterol and bad cholesterol. The good cholesterol is called high-density lipoprotein (HDL). The bad cholesterol is called low-density lipoprotein (LDL). In the bloodstream, cholesterol and triglycerides
Step 1 Determine lipoprotein levels- obtain complete lipoprotein profile after 9- to 12-hour fast. Abdominal obesity Waist circumference There are many lipid-lowering drugs on the market. The most common are listed below. Lipitor (atorvastatin calcium); Pravachol (pravastatin sodium); Zocor (simvastatin); and Crestor (rosuvastatin calcium). Lipitor is indicated to reduce elevated Total-C, LDL-C, Apo B and TG levels and to increase HDL-C in patients with primary hypercholesterolemia and mixed dyslipidemia. Pravachol is indicated to reduce elevated Total-C, LDL-C, Apo B and TG levels and to increase HDL-C in patients with primary hypercholesterolemia and mixed dyslipidemia. Pravachol is also indicated to reduce the risk of myocardial infarction, undergoing myocardial revascularization procedures and cardiovascular mortality with no increase in death from non-cardiovascular causes. It is also indicated to reduce the risk of total mortality by reducing coronary death; stroke and stroke/transient ischemic attack (TIA) and can slow the progression of coronary atherosclerosis. Zocor is indicated to reduce the risk of total mortality by reducing CHD deaths, non-fatal myocardial infarction and stroke, and need for coronary and non-coronary revascularization procedures. Patients with hypercholesterolemia Zocor is indicated to reduce elevated total-C, LDL-C Apo B, and TG, and to increase HDL-C. Crestor is indicated as a
Some topics in this essay:
HYPERCHOLESTEROLEMIA Hypercholesterolemia,
Apo TG,
LDL-C ApoB,
TLC Diet,
IDL LDL,
CHD Symptomatic,
CHD CHD,
HDL Cholesterol,
ATP III,
Risk Factor,
indicated reduce,
elevated total-c ldl-c,
10 20,
total-c ldl-c,
increase hdl-c,
reduce elevated,
available 10,
ldl goal,
elevated total-c,
available 10 20,
reduce elevated total-c,
tg levels,
hdl-c patients primary,
apo tg,
10 20 40,
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Approximate Word count = 966
Approximate Pages = 4 (250 words per page double spaced)
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