double helix
The double helix of the DNA is shown along with details of how the bases, sugars and phosphates connect to form the structure of the molecule. DNA is a double-stranded molecule twisted into a helix (think of a spiral staircase). Each spiraling strand, comprised of asugar-phosphate backbone and attached bases, is connected to a complementary strand by non-covalent hydrogen bonding between paired bases. (Watson, 1968) The bases are adenine (A), thymine (T), cytosine (C) and guanine (G). (Watson, 1968)"The stuff genes are made of."()In the early 1950's, British biophysicist Francis Crick and American biochemist James D. Watson determined the three dimensioned structure deoxyribonucleic acid (DNA) with the help of Maurice Wilkins and the test results from Rosalind Franklin's x-ray diffraction images.(Levine, 1997) A DNA molecule is really the blue print for the genetic, because it determines attributes of living things. With this major discovery came a great prize, the Nobel Prize. Watson and Crick both shared this honor and received the Nobel prize in 1962 physiology as medicine.(Watson, 1968) James Watson later wrote a novel called "The Double Helix" which was like a diary of how the discovery was made.(Lev
Crick is best known for his work in the discovery of the double helix, but since then he has made many other discoveries. After his discovery of the double helix, Crick went to work on finding the relationship between DNA and genetic coding. During this study with Vernon Ingram, they discovered the function of the genetic material in determining the specificity of proteins. In 1957, Crick began work with Sydney Brenner to determine how the sequence of DNA bases would specify the amino acid sequence in proteins.(Gamov, 1975) ine, 1997) Watson and Crick found the DNA diameter which is 20 A. The book displayed the hardships, conflicts, ethics, attitude, competition and unique theories which made this discovery more enjoyable. genetic code for proteins.www.genes.com Watson and Crick showed that they were not ethical on their journey for DNA. They stole ideas and put it in their own research, such as when Rosalind Franklin's hard work with X- ray diffraction and Linus Pauling's theory of the bonding bases. (Judson, 1986) Watson and Crick were really unethical when they stole her x-ray and never really credited her and Linus's failure was glorified by them. (Watson, 1968) They refused to give their work to any one else to research. One great example was when the greatest American chemist was denied a passport and Watson and Crick enjoyed this more than anything.(Watson, 1968) This was unethical, because the chemist could have helped them solve this dilemma sooner. In chapter 6, Watson enjoyed and even called this a tradition when one promises a funding agency that you will do one thing and then go into the lab and do something else.(Watson, 1968) This is a very unethical thinking, because the funding person is losing money on something which he has no interest for. In their era women's right was becoming strong, however, Watson still thought of them as low. Throughout the novel he gave Rosalind Franklin a hard time by insulting her looks, her thought and her scientific work. He never encouraged her or paid any attention. (Gamov, 1975) If Watson showed some compassion and ethics towards science and women, maybe the readers would not have criticized him.
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Approximate Word count = 2348
Approximate Pages = 9 (250 words per page double spaced)
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