Physicists from 1939 onward conducted much research to find answers to such questions as how many neutrons were emitted in each fission, which elements would not capture the neutrons but would moderate or reduce their velocity , and whether only the lighter and scarcer isotope of uranium (U-235) fissioned or the common isotope (U-238) could be used. They learned that each fission releases a few neutrons. A chain reaction, therefore, was theoretically possible, if not too many neutrons escaped from the mass or were captured by impurities. To create this chain reaction and turn it into a usable weapon was the ultimate goal of the Manhattan Project.

The Hiroshima model is known as a gun-barrel-type atomic bomb. Due to its long and narrow shape, the Hiroshima model was called "Thin Man" at first, but during the manufacturing process the original plans were modified, shortening the length and giving rise to the name "Little Boy." (Beyer 48).The energy released from the Hiroshima A-bomb was originally thought to be equivalent to the destructive power of 20,000 tons of TNT. Later estimates, however, put the energy equivalent to approximately 15,000 tons of TNT, based on damage done to buildings and research on the bomb’s composition. Despite the release of such enormous energy, it is believed that less than one kilogram of the 10 to 30 kilograms of uranium 235 housed in the bomb achieved fission.

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