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"Human Genome Project"

Early in 1990, the Human Genome Project (HGP) was formed. This 13-year effort was formed to analyze the human genetic inheritance in its original molecular format. The Department of Energy and the National Institutes of Health were the main research agencies involved with the HGP. These two agencies were involved in developing and planing the project in the US government. The Department of Energy and the National Institutes of Health were working together, a relationship was formed by the signing of a Memorandum of Understanding. This agreement was simply to coordinate research and technical activities related to the human genome. The goal of the HGP is to generate a series of tools that will change biological research.

In the beginning of the Human Genome Project, the initial plan was set for completion in a 15-year timeframe, making the project complete in the year 2005. Fortunately, newer and faster technological advances have accelerated the completion deadline to the year 2003.

The complete nucleotide sequence of human DNA is approximately 50,000 to 100,000 genes in the human genome. The Huma


Information required by a cell stored is in the nucleus. Encoded into the structure of the nucleus are DNA molecules called chromosomes. This information allows the cell to replicate, differentiate into all the different cells that comprise a human, interact with other cells, respond to threat and replace damaged tissue. An understanding of the information stored in the chromosomes will give biologists insight into how the cell functions. The basis of the HGP is the decoding of all information stored in the chromosomal DNA. This part of the project is known as DNA sequencing. There are 3 billion residues, or bases, in the human genome and the order of these bases that encodes the biological information. As a prelude to the main act of sequencing the human genome, many more simple organisms have their genomes sequenced. These include many bacteria and viruses as well as yeast.

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Approximate Word count = 1183
Approximate Pages = 5 (250 words per page double spaced)


  

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