About one in every 100,000 people are affected by a rare endocrine disorder called Addison’s disease. The disease occurs when the adrenal glands do not produce a sufficient amount of cortisol or aldosterone. Because of this, Addison’s disease is often sometimes called chronic adrenal insufficiency, or hypocortisolism. Cortisol is normally produced by the adrenal glands, which are located just above the kidneys. Its most important job is to help the body respond to stress. It also helps regulate the metabolism and maintain blood pressure. The hypothalamus and the pituitary gland regul