Klinefelter's Syndrome
Klinefelter’s syndrome is a genetic endocrine disorder that causes significant femaleness in men. It affects about one in five hundred to one in one thousand live born males. Klinefelter’s Syndrome is characterized by a lack of normal sexual development, infertility, and psychological adjustment problems. In their chromosome difference an extra “X” chromosome is present in the sex chromosome or the twenty-third chromosome. Klinefelter’s Syndrome is also known as “XXY Syndrome.” Klinefelter’s Syndrome was named after H.F. Klinefelter. He studied Klinefelter’s patients at Harvard. Klinefelter’s syndrome is caused by an extra X chromosome and affects only males. During Meiosis the 46 chromosomes separate producing two new cells with 23 chromosomes each. Before meiosis is completed the chromosomes pair with their corresponding chromosomes an
This hormonal imbalance is treated with testosterone injection, a synthetic form of testosterone. It is given once a month. The results of the treatment can be seen in the progression of physical and sexual development, including pubic hair, increase in penis size, beard growth, deepening of voice, and an increase in muscle build and strength. Also, many of the psychological characteristics appear to be benefited by the testosterone therapy. Benefits of testosterone therapy include higher male confidence, more energy and more endurance. Even with the testosterone therapy, Klinefelter’s patients remain infertile. d exchange information. In some cases, the Xs or the X chromosome and Y chromosome fail to pair and fail to exchange genetic material. Sometimes this results in them moving alone to the same cell, producing either an egg with two Xs, or a sperm having
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Approximate Word count = 585
Approximate Pages = 2 (250 words per page double spaced)
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