Hurler’s disease could quite possibly be considered as one of the most dangerous types of lysosomal diseases because it is not really detectable until 6 and 24 months after birth. Once the disease is recognized though many times it is too late considering that the individual is already mentally retarded. Children that are affected by this disease have enlarged stomachs because of the fact that their spleens have swollen up.
The skeleton also is affected by the lysosomal malfunction, suffers normally have hunched backs and stunted growth. Also the thorax becomes stiff which causes those affected