Pattern of Organization: Topical order.

Introduction: Imagine having resting and postural tremors, muscle slowness of movement, and postural imbalance to deal with on a daily basis, Well, that’s what people suffering from the crippling disease known as Parkinson’s.

Thesis/central idea: I’m going to explain a little about the Parkinson’s disease, tell the stories of some famous Parkinson’s sufferers, and the tell you where we are at right now on dealing with the disease and trying to find a cure..

Establish credibility: I’ve read through numerous articles and books on the disease and have found many interesting facts.

I. A. Parkinson’s disease is defined by as a disorder of the brain characterized by shaking and difficulty while walking, movement, and coordination.

B. The disease is associated with damage to a part of the brain that controls muscle movement.

C. Parkinson's disease was first described in England in 1817 by James Parkinson. The disease affects approximately 2 out of 1,000 people, and most often develops after age 50. It affects both men and

C. In their early days these cells, which are obtained from aborted fetuses and embryos created at fertility clinics, have the capacity to become any kind of human tissue. This means that they could conceivably replace cells lost in degenerative conditions. The thought is that in Parkinson's, these cells may play a role in restoring cells in the substantia nigra part of the brain, which the disease progressively destroys. Levodopa combined with carbidopa remains the gold standard for the treatment of PD. However, long-term use of levodopa is associated with the development of motor complications in as many as 80% of PD patients. The most disabling of these motor complications are the dyskinesias (or the loss of movement in the arms and legs).

III. A. The fight against Parkinson’s disease is a tough one, but it isn’t going without a challenge.

II. A. Like I said earlier, 2 people out of every 1,000 are affected and some of those happen to be famous public figures. The most popular among these sufferers are Muhammad Ali, Janet Reno, and Michael J. Fox.

E. Parkinson's disease is caused by the deterioration of the nerve cells of the part of the brain that controls muscle movement. Deterioration of this area of the brain reduces the amount of dopamine available to the body. Without dopamine, the nerve cells cannot properly transmit messages, and this results in the loss of muscle function. In addition to the loss of muscle control, some people with Parkinson's disease become severely depressed. Although early loss of mental capacities is uncommon, with severe Parkinson's the person may exhibit overall mental deterioration (including dementia, hallucinations and so on). Dementia can also be a side effect of some of the medications used to treat the disorder.

B. In August 2001 President George W. Bush gave limited federal funding for stem cell research. Stem cells can develop into many other types of tissue, which scientists believe could create new treatments for diabetes, P

Some topics in this essay:
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