Staphylococcus
In a healthy human, the internal tissues such as blood, brain, and muscle are generally free of microorganisms. On the other hand, the surface tissues, such as skin, all of the mucous membrane in the mouth, nasal cavity and intestinal tract can easily and readily become available for microorganism to colonize and grow. Depending on the location in the human body, different bacteria choose to grow on a specific location that provides the nutrition it needs, with optimum condition such as pH. There are many different bacteria that collectively are called normal flora, and live in the human body. Many of these bacteria are commensally living in humans, and some others are symbiotic. Commensal bacteria only obtain their food from the human, and do not harm or benefit the host, on the other hand symbiots not only get their food from the host, but in return they also become beneficial to the host in providing nutrition that human can not make, such as vitamin K. One of the most reco!gnized and extensively studied bacteria that often get more attention during the winter is Streptococcus. There are different strains of strep. Depending on their ability of hemolysis of blood agar, strep can be subdivided into a, b and g hem
The second best-known Streptococcus is group B strep. “Most human group B Streptococci inhibit the lower GI and female genital tracts and belong to the species Streptococcus agalactiae” (1-pp150). For that reason newborn babies are susceptible to group B strep infection. In some cases, mother can be vaccinated or even treated with antibiotic prior to pregnancy. The problem is, in most cases the infection does not show any symptoms. “If the mother, and therefore the baby, lack protective antibody, the Streptococci can invade the mucosa and, in some cases, enter the blood stream.”(1-pp150). Meningitis and neonatal sepsis are two diseases that are frequently caused by group B strep. Meningitis can also be caused by another strain of strep called Streptococcus salivarius. “Streptococcus salivarius is a common inhabitant of the oral musosa that has been associated with infection in different sites. Meningeal infection by this species, generally related to neoplasias or iatrogenia. olytic (1-pp143). There are many different laboratory tests that can be done to distinguish one strep from the other. Different treatments also have been developed to fight each strain of strep. Different strains of Streptococci produces different hemolytic results. For that reason, the first test that can separate a beta hemolytic from alpha is to perform blood agar test. “Sheep blood is the blood of choice for primary isolation. It contains a factor that inhibits growth of Haemophilus haemolyticus, which is an organism commonly present in “normal” throats and is easily confused macroscopically with the appearance of beta hemolytic streptococci ”(2). Groups A, B, C, F and G are usually beta hemolytic. These groups are equipped with the toxic enzyme, hemolysin, that has the ability to completely lyse the red blood cell (erythrocyte), creating a clear zone around the colonies. On the other hand, alpha hemolytic strep such as group D and S. pneumoniae are alpha hemolytic. They also lyse red blood cells, but they do it partially, leaving a greenish zone around the colonies. Streptococcus is catalase negative. The catalase test is often used to distinguish between strep a! Bacteria replicate in a fast pace, and have a high rate of mutation. For that reason, more and more strep strains are becoming drug resistant. Recently in mice experiments in a lab setting “administration of carboxyfullerene via the peritoneum and air pouch at 3 h post-S. pyogenes infection was able to protect 33% of mice from death. Furthermor
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Approximate Word count = 1702
Approximate Pages = 7 (250 words per page double spaced)
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