Osteopontin Gene
The immune-system gene, Osteopontin, plays an important role in the progression in Multiple Sclerosis. After different studies were done in many different labs at different Universities, it was found, or discovered, that Osteopontin, and other genes, where found in Multiple Sclerosis patients in the damaged area of their brain tissues, as oppose to the good brain tissues where the gene was not found. This test was not only done to human beings, but to mice as well. The same tests were done on them at Universities, just as the human tests went. With much research, it was found that Osteopontin was found in the areas of the myelin, and damage during “relapse and remission.” Myelin is a “substance” that has numerous amounts of lipids and proteins, that which forms a layer around the nerve fibers. A good example of myelin is insulation. Relapse and remission is when like Multiple Sclerosis symptoms get worse or new symptoms appear. These tests prove that Osteopontin is important in the development of Multiple Sclerosis, and to help to determine how the disease progresses whether it progresses slowly or quickly. There is still a lot of research to be done in order for these tests to be one-hundred per
detailed process. Osteopontin contributes in the bone part and in this part of the body has calcium and phosphate. Calcium and phosphate are “regulated primarily by paratyhyroid hormone and vitamin D.” This all takes place around the gut, bone, and kidney, for an increase of some of the calcium. This contributes in the disease osteoporosis, but I am looking at the gene from the Multiple Sclerosis point of view, so from my perspective it really wouldn’t matter. But this is how the gene works in metabolism. It is involved in bone metabolism.
Some topics in this essay:
Multiple Sclerosis,
Paramethoxyamphetamine PMA,
Mus Musculus,
B-cells Osteopontin,
PNS Schwann,
multiple sclerosis,
Gene Project,
Mice Osteopontin,
schwann cells,
Sclerosis Multiple,
Uropontin ETA,
multiple sclerosis multiple,
Secreted Phosphoprotein,
sclerosis multiple sclerosis,
relapse remission,
mice osteopontin,
progression multiple,
sclerosis multiple,
bone metabolism,
sclerosis patients,
multiple sclerosis patients,
progression multiple sclerosis,
involved bone,
helps scientists,
involved bone metabolism,
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Approximate Word count = 1190
Approximate Pages = 5 (250 words per page double spaced)
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