... with BMIs less than 20. Women have a considerably higher quantity of leptin than men, but when being compared by percent of body fat, men and women have comparable leptin levels. The instructions to make leptin are found in the obese (ob) gene, which was cloned in mice. In 1994, it was proven that the ob gene in mice made leptin, which was actually produced in the fat ... and then it would be released into the bloodstream. Researchers published a study documenting that ... there was a thirty percent weight loss in genetically obese mice that were given daily injections of leptin for tw...

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• Approx Pages: 2

... appetite but also an increase in energy expenditure and other actions related to energy homeostasis, one must consider the other functions of leptin. Original parabiosis of ob/ob and db/db mutant mice with wild-type mice suggested that there was a factor that ob mice lacked that caused them to gain abnormal weight compared to wild-type mice, and that db mice were resistant to this factor (Coleman et al ... treatment appears to accelerate reproductive maturation in women and cause an earlier onset of the oestrous cycle, and in men, a surge of leptin is seen in at the onset of puberty. In...

• Word Count: 3450
• Approx Pages: 14
• Grade Level: Undergraduate