... not cause insertional mutagenesis so that normal gene function (of other genes) is impaired. Third, there must be no lingering effects from the original gene deficiency. Finally, the gene insertion procedure must not induce genetic side effects. Moreover, there must be sufficient assurance that the manipulation will not be lethal to the preimplantation embryo and there needs to be a high effficiency ... nervous system is the target of the pathology, and the clinical outcomes are marked by profound disability and premature death. Here, somatic cell gene therapy, if applicable, would prob...

• Word Count: 1720
• Approx Pages: 7
• Grade Level: Undergraduate