... trial participants, one can feel that IRBs should truly focus more on the magnitude of change in disease rates among the population when calculating prospective benefits and risks connected with investigational chemo-prevention agents. The recently completed STAR trial compared raloxifene to tomoxifen to investigate whether an equivalent benefit could be reached with fewer grim side ... to overestimate their cancer risk (Hampton 1). The term "prevention" has truly created such positive thoughts, making eligible subjects overestimate possible benefits and not wholly realize the harmful ri...

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• Grade Level: Graduate