... are narrowed or blocked so that blood flow to the muscle can't increase to meet the need for more oxygen, ischemia may occur, resulting in pain. Usually, angina results from coronary artery disease. But it can result from other causes, including abnormalities of the aortic valve, especially aortic valve stenosis (narrowing of the aortic valve), aortic valve regurgitation (leakage of the aortic ... enlargement also may reflect the heart muscle damage itself. Enlargement after a heart attack suggests a worse prognosis than a normal heart size. A blood clot is the most common cause of a bl...

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