... necessary to achieve the purpose of the work. Refinement- keeping pain, suffering or other harm as low as possible. The harm-benefit analysis (5) states animal-based scientists as well as ethics committees must: 1. Make sure that any harm caused is as low as it can be. 2. Make sure that the expected benefits of the work are achievable and are as great ... they grow and spread. The development of chemotherapy was tested on rodents, monkeys and rabbits in 1950. Forty years later, in 1990, scientists began closing in on the genetic and environmental factors that lead to breast cancer, whic...

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• Approx Pages: 15
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