1. Hemophilia
Males have one X chromosome and one Y chromosome, while females have two X chromosomes. ... While one of the X chromosome in a female may contain a nonfunctional clotting factor gene, her other X chromosome will usually compensate for the lack of or nonfunctionality of the clotting factor. ... Hemophilia was first noticed in the Jewish community, when infant Jewish boys were circumcised and their blood failed to clot during the procedure. ...
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