1. The Cystic Fibrosis Gene
... by epithelial cells.9 As a result of this diffusion of water, airways become blocked and pancreatic proteins turn inactive. An Account of the Absorption and Secretion of Cl-, Na+, and Proteins An inward, electrochemical Na+ gradient is generated by the Na+, K+-ATPase pump located in the basolateral membrane (the cell side facing the organ it is lining). A basolateral co-transporter then uses the ... done in such a way that when the apical Cl-channels within the membrane spanning domain open, Cl- diffuse passively with their gradient through the cell membrane.4 In pancreatic duct cells, a...
- Word Count: 2162
- Approx Pages: 9