... function (ability to sense blood glucose levels, insulin synthesis, and insulin secretion), proinsulin and insulin molecular structures, insulin receptors, hepatic synthesis of glucose, glucagon synthesis, and cellular responsiveness to insulin stimulation. These genetic abnormalities combined with environment influences, such as obesity; result in the basic pathophysiologic mechanisms of ... syndrome that the body can not sufficiently respond to insulin and has an impaired pancreatic production of insulin. Obesity is a huge contribution to diabetes and the development of insulin resista...

• Word Count: 1292
• Approx Pages: 5
• Has Bibliography
• Grade Level: Undergraduate

... derangement of glucose metabolism alone, but also involves metabolism of proteins, lipids, nucleic acids, and complex derivatives of these major groups" (p. 1). Treatment and control of diabetes ... in the treatment of diabetes (Kozak, 1982). According to Armstrong and Wakat (1985), "the exciting feature of exercise for the diabetic is that it can improve glucose control as well as cardiovascular and respiratory function" (p. 8). Insulin sensitivity is increased during bouts of ... the American Academy of Orthopaedic Surgeons (1991), Without insulin, the body cannot metabolize glucose, a...

• Word Count: 2938
• Approx Pages: 12
• Grade Level: Undergraduate

... towards the glucose stimulus decreases, contributing to the hyperglycemia. Some of the effects on the body of glucose toxicity include (Center for Disease Control on-line, 2002): • Cause impaired cell function/damage/starvation • >115 mg/dl is threshold for pancreas • >180 mg/dl is threshold for nerve cells • Eventually leads to hypoinsulinemia and other complications • Markers of elevated plasma insulin levels • Increase in serum ... that may result from hyperinsulinemia include stimulation of fat storage, increase in appetite, increase in sodium reabsorption in the kidneys...

• Word Count: 1602
• Approx Pages: 6
• Grade Level: Undergraduate