1. Reproductive Endocrinology
... menstrual function requires GnRH pulsatile secretion in a critical range of frequency and amplitude. The pulses of GnRH appear to be directly under the influence of dual catecholaminergic system: norepinephrine facilitatory and dopamine inhibitory. The catecholamine system can be influenced by endogenous opioid activity. The feedback effects of steroids may be mediated through this system via catechol steroid ... GnRH antagonists bind to the GnRH receptors and provide competitive inhibition of the naturally occurring GnRH. Thus GnRH antagonists produce an immediate decline in gonadotrop...
- Word Count: 9441
- Approx Pages: 38
- Grade Level: Undergraduate