Substances like 3,4-methylenedioxy-N-methylamphetamine (MDMA, better known as ecstasy), cocaine, methamphetamine, and d-lysergic acid diethylamide (LSD/acid) have been identified as party drugs because of their link to club and partying culture among young adults and teenagers. All of these drugs are considered being stimulants which is a class of psychoactive drugs. All our thoughts, actions, memories, and behaviors result from biochemical interactions that take place in and between neurons. Drugs that affect these processes are, in general, called psychoactive drugs.1 By altering our neurotransmitters these psychoactive drugs could elevate mood, increase feelings of well-being, amplify energy, and along with heighten alertness to surrounding elements. Based on their ability to produce a state of euphoria for the users, they are commonly referred to as "uppers". All of the psychoactive drugs listed above are labeled as illegal stimulants under different controlled substances law in almost every country during the early 1970s. Despite all the effort to control these psychoactive drugs, one of them managed to fly under the radar for over forty years without being outlawed until recently, 3,4-methylenedioxy-methylcathinone, bk-MDMA(Methylone, also known as M1). .
The chemical structure of Methylone is a close structural analogue to its more popular brother MDMA, differ only by an addition of B-ketone group. Methylone was investigated for its psychoactive properties during the 1970s. Shulgin et al and his partner Jacob patented the drug as an antidepressant and antiparkinson agent in the middle 1990s. Due to the similarity of the structure to MDMA, Methylone produce a strikingly close effect on human body to its brother. Just like MDMA, Methylone is psychologically substances that are able to help one to identify with the feelings of others or feel a sense of connectedness with others and affect an individual's physical of sensation as the same time.