The human body is an incredibly complex organism that is susceptible to many different disease. Some of these diseases only effect 1 in 100,000 or 200,000 people and becomes incredibly difficult to either treat or cure. Some of these diseases have not been adopted by the pharmaceutical industry because there is very little financial incentive in order to cure these diseases, these diseases are called orphan diseases. An orphan disease could be a rare disease that effects fewer than 200,000 people. Other orphan diseases are common diseases that have been ignored in developed countries because modern medicine has effectively eradicated the disease. New rare diseases are discovered every year due to variations or defects in genes. Other orphan diseases can come from environmental or toxic conditions. The process for diagnosing orphan diseases are still poor. Patients who have a rare disease will often see a physician about 7 times before even receiving a diagnosis. .
Van der Woude syndrome is an orphan disease that affects the development of the human face. Often people who are born with this syndrome often suffer from a cleft lip, a cleft palate or either. People with Van der Woude syndrome often suffer from speech problems due to the cleft palate and lip. The orphan disease syndrome is estimated to effect 1 in 35,000 to 1 in 100,000 people based on data from Europe and Asia. Van der Woude syndrome in children will affect about one of 40,000 to 100,000 infants. This syndrome is believed to be the number one cause of cleft palate and lip. The syndrome is caused by a single gene variation in the human body. The gene that is mutated which causes the Van der Woude syndrome is called interferon regulatory factor 6, IRF6. This disease is an autosomal dominant condition, a condition that is autosomal dominant only needs one parent to have the abnormal gene to for the disease to be passed down. The Van der Woude syndrome can be treated and survivable with the availability of adequate health care in the area.
Henry van der Luyden. ... The last family described is the van der Luydens. ... Mingott's seeking of the advice of the van der Luydens. ... Mr. van der Luyden then responded with their answer against the veto. ... Both the actions of the van der Luydens and the other characters" reactions provide much information about the van der Luydens themselves. ...
In "This is a Naked Lady", Van Der Leun touches on the controversial topic of pornography on the net. ... Creating a stylistic timeline, Van Der Leun shows the series of events and cultures which helped shape porn to be what it is today. ... Analyzing earlier societies, Van Der Leun reveals the artistic aspect of pornography to Neolithic paintings, comparing similar modern day images to that of "prehistoric sculptures of females with pendulous breasts and very wide hips" (Van Der Leun 476). ... The woman in Van Der Leun's short story logs onto the online site The Source as an individual s...
Van der Lubbe was then arrested and charged. ... I think that the Nazis used Van der Lubbe as a scapegoat. ... Van der Lubbe could have lied in Source B, at his trial in 1933, to cover for the Nazi Party. ... In Source G, Karl Ernst, a leader of the SA explains that they "used van der Lubbe. ... The Nazis could have easily directed the Fire, using van der Lubbe as a set-up. ...
ABSTRACT The aims of this lab report is to determine whether there are differences in temporal resolution along the horizontal and vertical meridians, and to replicate the earlier findings by Cass and Van De Burg (2014) that contextual flicker interferes with temporal order judgement. ... According to Cass & Van der Burg (2014) experiment temporal resolution in the visual field is significantly limited by the rate at which time is perceived. ... The aims of this lab report is to; replicate the earlier finding by Cass and Van der Burg (2014) that contextual flicker interferes with temporal orde...
One common criticism of modern architects such as Mies van der Rohe and Walter Gropius is that while their goals might have been laudable, the execution and physical manifestation of their beliefs is somehow disconnected from the culture in which it grew out of. ... The Functionalists included Gropius, Mies van der Rohe and others. ... This "International Style" came to embody capitalism, since it favored huge glass and steel office buildings, such as the Seagram Building (1957) pictured below, by Mies van der Rohe along with Phillip Johnson. ... Van der Rohe's furniture designs are clos...
There are three types of intermolecular forces : - Van Der Waals' Forces : a temporary dipole that occurs in a molecule, attracting another molecule of the same compound to itself, due to one of the molecules having an electron repel the electron in the other molecule, creating a positive-negative pole and attraction. ... These forces are stronger than Van der Waals' forces, but still relatively weak... Ten times stronger than Van der Waals' forces, they occur when the electron density changes around the atoms : the electronegative atoms gain electron density whereas the hydrog...
Within the two given articles, Van Der Graaf Generator (hereafter Article 1), and Introduction (hereafter Article 2), each of these elements can be dissected in order to obtain a clearer understanding of the texts as a whole. ... At first glance it can easily be determined that the text is informative, relating the story of Van Der Graaf Generator in a chronological, biographical style. ... Article 1 attempts to make a series of meanings regarding Van Der Graaf Generator, as well as the music scene of the time. ... One of the central meanings of the article would seem to be that Van Der Graaf ...
Before starting my essay on Master Mies van der Rohe, I would like to appreciate this opportunity to view great exhibitions comprising his most of works. ... By the way, seeing his works according to chronology as they set up at the museums, I found out that the two exhibitions of Mies van Der Rohe at the Moma and the Whitney demonstrates with a clarity the evolvement of Mies. ... In sum, the exhibition was a great opportunity to view through a panorama of how the Great master Mies van Der Rohe was born and fostered up until his mature stage in coexistence of historicism and modernism in Eu...
In particular, literature demonstrates a growing interest on the issue of whether men and women behave differently in leadership roles (Statham, 1987; Pounder & Coleman, 2002; Eagly & Johannesen-Schmidt, 2001; Carless, 1998; Burke & Collins, 2001; Davidson & Ferrario, 1992; Park, 1996; Van Engen, Van der Leeden & Willemsen, 2001; Eagly & Johnson, 1990; Powell & Graves, 2003). ... While some researchers exploring gender disparities found a lack of support for the notion that women and men utilize different leadership styles (Van Eagen, Van der Leeden & Willemsen, 2001; Pounder & Coleman, 2002)...
