1. Social issues
... serving as a model for related human encephalitic viruses. Our laboratory has extended the use of Sindbis virus as a tool to study the role of programmed cell death in a variety of human disorders. We found that Sindbis virus infects and induces classic apoptotic cell death in a variety of cultured cell lines and in cultured primary neurons. Despite its broad tropism in cell culture ... virus infection is not understood. Similarly, it is not understood why mosquitoes and mosquito cell lines often fail to under go programmed cell death upon infection with Sindbis virus. To study cellular...
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- Grade Level: Graduate