1. Free Radical and Mitochondrial Dysfunction
The most common ROS found in biological systems are hydrogen peroxide (H2O2), superoxide anion (O2 -), and hydroxyl radical ( ·OH). ... Randerath et al., 1995 state that even though much of the damage is removed by repair systems, oxidative DNA lesions nevertheless accumulate with age, and this probably plays an important role in the aging process (cited by Wickens, 2001) ROS Exerted Effect on Mitochondria Reactive oxygen species are created in multiple cellular compartments, but approximately 90% of cellular ROS forms in mitochondria during the normal process of oxidative phosphoryl...
- Word Count: 1154
- Approx Pages: 5
- Has Bibliography
- Grade Level: Undergraduate