1. History of the GC/MS
... , and measuring molecular ions according to their mass-to-charge ratio. The ions are generated in the ionization source by inducing either the loss or the gain of a charge (e.g. electron ejection, protonation, or deprotonation). Once the ions are formed in the gas phase they can be electrostatically directed into a mass analyzer, separated according to mass and finally detected. The ... sequencing of peptides and proteins, studies of non-covalent complexes and immunological molecules, DNA sequencing, and the analysis of intact viruses. In the 1990's, mass spectrometry hit the mainstream c...
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- Grade Level: Undergraduate