Victor abandons his loved ones in his thirst for creation. Walton says, "These volumes were my study day and night, and my familiarity with them increased the regret which I had felt, as a child, on learning that my father's dying injunction had forbidden my uncle to allow me to embark in a seafaring life" (Shelley 29). Walton still pursues his dream of living on the sea and exploration yet has left his sister Margaret. This is similar to how Victor leaves Elizabeth for his studies. The creature is shunned by all who see him. He tells Victor, "Who can describe their horror and consternation on beholding me?.Cursed, cursed creator! Why did I live? Why, in that instant, did I not extinguish the spark of existence which you had so wantonly bestowed?" (Shelley 121). The creature wishes he were dead in that moment. However the Creature and Victor will forever be tied together. Frankenstein and Victor are in constant pursuit of and flight from each other for the remainder of the story until Victor's death. These circumstances tie in with Mary Shelley's feelings of abandonment from her mother's early death to her own miscarriages and loss of a child. Mary's father treated her as a step child increasing her feelings of abandonment, "regardless of Mary's devotion to him, Godwin kept her at arms length" (Mellor 13). .
Mary Shelley created Frankenstein as a way to release her pain from losing children and her unfulfilled desire to be a mother. Mary ran off with Percy when she was just 16 years old and she became pregnant almost immediately. Percy gave Mary a feeling of worth that her father had not given her; she clung to that feeling of belonging and left her family for him despite the stigma surrounding their circumstances. Percy was still married at the time, this created great controversy within the family and Mary's father did not speak to her for over two years.