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Double Helix

            
            
             James Watson began his road to triumph in discovering DNA in the fall of 1951 when he visited the Cavendish laboratory of Cambridge University. He went to Cambridge to join a small group of physicist and chemist who were working on the three dimensional structures of proteins. His colleges were Francis crick, Max Perutz, and sir Lawrence Bragg. Crick was a very well known man sometimes categorized with Rutherford and Bohr. Crick had a very quick and penetrating mind, his colleges often sought after his advise. Crick was working with Perutz who was an Australian born chemist. He had been working on an X-ray diffraction and had been collecting it from hemoglobin crystals for over ten years. Helping Perutz was Sir Lawrence Bragg; Bragg was the director of Cavendish. Bragg was a noble prizewinner and one of the founders of crystallography. Before Watson's arrival to Cambridge Crick had only thought about DNA. At this time there was some evidence that DNA would unravel the true secret of life, however, it was still believed that proteins were the real mystery behind the true secret of life. There were still many scientists who believed that genes were protein molecules, and that DNA was too inconclusive. .
             At this time Francis was not prepared to jump into the world of DNA. Its importants did not seem efficient enough to abandon the world of proteins. Over time Crick and Watson began paying more attention to DNA and became more interested. Finally Crick devoted more of his time to DNA and slowly forgot about proteins. Once a door opened for Watson and Crick they began looking into it. After much time in a laboratory Watson and Crick found that proteins were no longer what they thought they could be and that DNA was indeed the basis of life. It was still very skeptical but they believed their research was going to prove the structure of DNA. .
             As their research went on Francis saw that it was hopeless and not going anywhere so he went back to proteins.


Essays Related to Double Helix

1. The Double Helix

As you read the cover of The Double Helix, you are bound to find that the book is "a personal account of the discovery of the structure of DNA," but the story is far more than that. ... The Double Helix is the story of James D. ... Throughout the story of The Double Helix, Rosy is Watson's antagonist. ... But whatever the case, Rosalind Franklin played an enormous role in the discovery of the double helix. Truly the narrative of The Double Helix, is one sided. ...

  • Word Count: 1078
  • Approx Pages: 4
  • Grade Level: High School

2. double helix

Double Helix The double helix of the DNA is shown along with details of how the bases, sugars and phosphates connect to form the structure of the molecule. DNA is a double-stranded molecule twisted into a helix (think of a spiral staircase). ... (Watson, 1968) James Watson later wrote a novel called "The Double Helix" which was like a diary of how the discovery was made.... (Watson, 1968) In the movie "The Race for the Double Helix," Watson and Crick rejoiced in the failure of Pauling's model of DNA. ... However, in "The Double Helix" there was a new image which I have never seen...

  • Word Count: 2348
  • Approx Pages: 9
  • Grade Level: High School

3. DNA

Both scientists showed that DNA was a helix. ... He was able to fit the bases into a double standard phosphate sugar backbone helix with phosphate sugar backbone on the outside. ... When Rosalind Franklin learned that the Cavendish group had discovered the double helix she was happy that it had been discovered and her 1951 suggestions had been correct. ... DNA Structure DNA is double stranded. ... Finally, when the base pairs form they twist the polynucleotides into a helix in which there are 10 base pairs for every one turn of the helix: double stranded DNA is a double helix. ...

  • Word Count: 1535
  • Approx Pages: 6
  • Has Bibliography
  • Grade Level: High School

4. Central Dogma

Then chemist Erwin Chargaff discovered that the %'s of DNA were equalities of A = T and G = C, which are now known as Chargaff's rules, which was then explained by the discovery of the double helix by Francis Crick and James Watson. There double helix creation not only explained Chargaff's findings but it also suggested the basic mechanism of DNA replication, which is the big part of Central Dogma. Because of the double helix, it can separate into to DNA strands, and "new" nucleotides then match up with there corresponding nucleotide (T with A and G with C). These nucleotides...

  • Word Count: 926
  • Approx Pages: 4
  • Grade Level: High School

5. James Dewey Watson

(accessexcellence.org) In 1953, Watson and Crick proposed that the structure of DNA or deoxyribonucleic acid, of which all living matter is made, was a winding helix in which pairs of bases(adenine paired with thymine and guanine paired with cytosine) held the two strands together. ... After solving the double helix, Watson went on to work in Molecular Genetics, specifically viruses and RNA, another genetic information carrier. ... Watson wrote The Double Helix: A Personal Account of the Discovery of the Structure of DNA, which was first published in 1968 and has never been out of print. ....

  • Word Count: 594
  • Approx Pages: 2
  • Grade Level: High School

6. DNA

They link together to form chains, which are arranged like a twisted ladder called a double helix. ... The two main scientists who discovered the double helix of DNA are James Watso and Francis Crick. ... In 1953 he and James Watson discovered the secret to life, the double helix of DNA. ...

  • Word Count: 395
  • Approx Pages: 2
  • Grade Level: High School

7. heredity

Watson and Francis Crick proved that most DNA consists of two polynucleotide chains that are twisted together into a coil, forming a double helix. Watson and Crick also discovered that in a double helix, the pairing between bases of the two chains is highly specific. ... When DNA replicates, the two strands of the double helix separate from one another. ... The new DNA strand stays attached to the old one through the hydrogen bonds, and together they form a new DNA double helix molecule. ... (Grolier Encyclopedia, 1992) For transcription to take place, the RNA polymerase enzyme is needed ...

  • Word Count: 931
  • Approx Pages: 4
  • Grade Level: High School

8. Human Genome Project

In 1952, Rosalind Franklin photographed crystals of highly purified DNA showing a twisted helix. The bases, perpendicular to the length of fiber, have sugar-phosphate molecules on the outside of the helix. ... With this information, James Watson and Francis Crick discovered the true structure of DNA in 1953 and created a 3-D model showing the double-helix (Figure3). ... Before replication, proteins pry the double helix open at the replication forks, where unwinding and replication take place. DNA helicase enzymes then bind and move along the double helix in opposite directions from the ori...

  • Word Count: 2575
  • Approx Pages: 10
  • Has Bibliography
  • Grade Level: Undergraduate

9. dna

Watson and Francis Crick proved that most DNA consists of two polynucleotide chains that are twisted together into a coil, forming a double helix. Watson and Crick also discovered that in a double helix, the pairing between bases of the two chains is highly specific. ... When DNA replicates, the two strands of the double helix separate from one another. ... The new DNA strand stays attached to the old one through the hydrogen bonds, and together they form a new DNA double helix molecule. ... (Grolier Encyclopedia, 1992) For transcription to take place, the RNA polymerase enzyme is needed fir...

  • Word Count: 1313
  • Approx Pages: 5
  • Grade Level: High School

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