1. Target Liposome to a Particular Tissue
... are interrelating with a cell surface receptor that is endocytosed, leading to immunoliposome internalisation upon immunoliposome-cell interaction (Daan, et al, 2003). Thus, for a victorious action of the liposome-associated drug, escape from the endosome is vital because many drugs are inactivated when the endosome matures from the endosomal state into a lysosome. For endosomal ... escape, fusogenic peptides (often derived from viruses such as influenza virus) have been proposed or, alternatively, pH-dependent liposomes are used that destabilize the endosomal membrane when the pH drops...
- Word Count: 650
- Approx Pages: 3
- Grade Level: Graduate