... one day be readily available. The Dopamine Hypothesis Dopamine is a chemical in the brain that is either stimulated or prevented from being released by the terminal buttons into the synaptic cleft (the junction between nerve cells) in neurons. Stein and Wise constructed a neuronal model in 1971 to hypothesize what the chemical reasoning behind schizophrenia was. Together, they composed the DBH Model ... ...

• Word Count: 3057
• Approx Pages: 12
• Grade Level: Undergraduate

... through interaction with plasma membrane monoamine transporters, namely, the dopamine, serotonin, and norepinephrine transporters. The normal function of these transporters is to provide rapid removal of neurotransmitters from the synaptic cleft to permit repetitive synaptic firing (Gainetdinov, 2001). Dopamine has been strongly implicated in the control of locomotion, particular attention has been given to the interaction of these drugs with the ... ...

• Word Count: 3913
• Approx Pages: 16
• Has Bibliography
• Grade Level: Undergraduate

... signal and communicate. These substances are kept in vesicles located on the axon of the neuron. When a particular message triggers the release of these chemicals, they pass into the synaptic cleft which separates one axon from the dendrites of another neuron. This change in chemical gradient is then used by the next neuron to pass on the signal. There are many ... ...

• Word Count: 2595
• Approx Pages: 10
• Has Bibliography