Autopsy evidence has shown the numerous course of sudden infant death was due to toxicological evidence due to cocaine exposure. .
In addition, there is an argument amongst researchers that prenatal cocaine exposure may leave anomalous related consequences affecting the fetus sensory, cardiovascular and genitourinary systems. Furthermore, studies conducted on a controlled group of infants exposed to maternal cocaine increase showed a large quantity of strabismus (the alignment of the eyes) and extensive abnormalities and diseases to the eyes in premature babies. .
Cocaine infusion during pregnancy has also caused deformity to the auditory system of the fetus. Advance studies by Tan–Laxa, Sison-Switala, Rintelman and Ostrea (2004) examine the relationship of the auditory brain responses (ABR). The research indicated that new born babies exposed to (PCE) were inactive for long periods which pronounce defects in the outer auditory system in both ears. According to Lester et al (2003), the auditory brain response had an extension in neutral transmission. Likewise, Salamy and Eldredge et al (1994) found that infants exposed to cocaine had abnormal auditory brain responses which had a slow delivery in transmitting information.
An analysis done by researchers established that prenatal cocaine exposure has affected the cardiovascular system. However urine test has shown positive signs of metabolite in the infants' urine. In addition, researchers found an increase occurrence in cardiovascular disorder within the neonates. An evaluation undertaken in neonates exposed to cocaine indicated that the measured heart rate variability (HRV) was lower and also in the vagal tones. The research showed that the neonates exposed to excessive cocaine exposure compared to those with a minimum exposure had a significantly unusual vagal tone during the period two to six months. Maternal use of cocaine during the late stage of pregnancy can cause cardiovascular problems to the neonate.