and egg cells). The difference between replacing defective genes in germline and somatic .
cell therapy is that , in the germline cells (which contribute to the genetic heritage of the .
offspring). Gene therapy in germline cells have the ability to affect not only the individual .
being treated, but also their children as well. Germline therapy would change the genetic .
pool of the entire human species, and future generations would have to live with that .
change. But due to the difficulties and problems of germline therapy , it's unlikely that .
germline therapy would be tried on humans in the near future. Over 50% of gene therapy .
experiments are for the treatments of various cancers such as head and neck, ovarian, or .
metastatic cancers. For an example if you have a genetic diseases in which a single .
known gene does not function properly , such as sickle cell anaemia , thalassaemia and .
Lesch-Nyhan syndrome, are most suitable to be treated with the gene therapy. There are .
two types of gene therapy in curing these diseases, patient therapy and embryo therapy. In .
the process of the patient therapy, the first step is the defective or damage gene and to .
keep people who is infected away from others to prevent the spread of a contagious .
disease of the two genes that complement each other . To obtain correct gene action, it .
may be necessary to put it into the correct site on the host (or another organism, where a .
plant or animal that lives on or in another, lives) cell chromosome, or even to delete the .
defective gene , and the DNA can then be replicated (or to reproduce exactly an organism, .
genetic material, or a cell.)each time the host cell divided. But if the new cell is injected .
directly into the patient's body, it will be depended on the body's immune system that .
will recognize it as foreign and target it to be destroyed along with the healthy DNA that .
it is carrying. So the cells extracted from the patient are to be treated and adding the new .
