1. Mitchondrial DNA in Aging and Disease
... well as thirteen polypeptides found in the electron transport chain, such as the transfer proteins and ATP synthase. Replication of mtDNA is performed by a special form of DNA polymerase called DNA polymerase gamma. Interestingly, DNA polymerase gamma does not have any proof reading during mtDNA replication. Also, mitochondria do not have any of the efficient repair mechanisms that the nucleus has for nuclear ... under two categories: 1) inherited and 2) caused by random somatic mutations throughout life. In the case of an inherited mtDNA-related disease, it is inherited from the mother...
- Word Count: 2319
- Approx Pages: 9
- Has Bibliography
- Grade Level: Undergraduate