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HIV, Reverse and Transcriptase Inhibitors


            
             This experiment compares the effectiveness of reverse transcriptase inhibitors and protease inhibitors. A total number of 150 HIV-1/HIV-2 patients will be examined. The processes of examination will be done through laboratory test procedures. Each patient will begin taking medications administered to them starting from January 1st and their blood will be drawn for lab testing on the first of every month for a period of one year. At the end of the year, I am expecting to see notable changes in all of the participants' health. However, this experiment focuses more on the effectiveness of how best these inhibitors work. .
             Introduction.
             Over a quarter century ago, doctors and scientists in the western hemisphere first learned about a deadly virus called Human Immunodeficiency Virus (HIV). Initially, it seemed like HIV affected mostly gay homosexual males until it was seen otherwise. The symptoms of this disease were not static, meaning that there were several symptoms that resembled the symptoms that are usually exhibited in other diseases and illnesses. One early notable factor was that patients with this disease found it hard to get better because their immune system was highly suppressed by the virus. I.
             It is significant to know that our immune system is made up of mast cells, macrophages, plasma cells and leukocytes (or white blood cells). Leukocytes are made up of mostly immune cells which are NK cells, B cells, T cells and the Helper T cells. In general, these cells are supposed to help the body fight against bacteria, antigens and various types of viruses. But unfortunately, the HIV virus attacks one specific leukocyte cell called the Helper T cells. These helper T cells emit chemical signaling that help to notify the actions of B cells and T cells in the presence of an infection. III.
             In other to understand what HIV virus does and how it attacks the human body, researchers learned that HIV is a Ribonucleic Acid (RNA) virus that attacks the immune system through the following steps.


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