1. Social issues
... cell lines and in cultured primary neurons. Despite its broad tropism in cell culture, sindbis virus is profoundly neuronotropic in the brains and spinal cords of mice. Sindbis virus also induces apoptosisof neurons in mice, with young mice being generally more susceptible to neuronal apoptosis and fatal infections than older mice. The mechanisms by which some ... is not understood why mosquitoes and mosquito cell lines often fail to under go programmed cell death upon infection with Sindbis virus. To study cellular genes that modulate the outcome of a Sindbis virus infection in vivo, ...
- Word Count: 376
- Approx Pages: 2
- Grade Level: Graduate