Jackson was determined to defeat Adams in the election of 1828, and now he felt he had an issue that would help him win. Jackson, again running for the Presidency in 1828 was determined to win. His followers attacked Adams (who was running too) of the "corrupt" bargaining he had allegedly made with Henry Clay during the election of 1824. Adams responded by attacking Jackson with his marriage affair with Rachael Jackson. Soon thereafter, she died of a heart attack. Andrew Jackson was convinced it was the fault of Adams and his administration and never forgave them for it. .
Jackson was strongly opposed to the idea of having the Bank of the United States. He saw the removal of the bank as a perfect opportunity to strike back at Henry Clay, who was pro bank, for the actions that took place during the election of 1824. Biddle, the president of the Bank of the United States, saw that the banks charter would soon expire. Knowing that Jackson would not renew the charter in 1836 when it would run out, tried to prematurely renew it. After meeting with Henry Clay, Clay passed a bill through the House of Representatives for the re-charter of the Bank, hoping to slip it by Jackson. When the re-charter reached Jackson, it was quickly vetoed and sent back to congress, where a two-thirds majority failed to be reached. Soon after, The Bank of the United States was closed. Federal funds were placed in selected state organizations called Pet Banks. Jackson had used his presidency for his own personal gain. He had revenge over clay for the corrupt bargain and for the death of his wife by closing the Bank of the United States, which he thought was unconstitutional. .
Another blow was delivered to Clay when he proposed that is was necessary to construct the Maysville Road in Clays home of Kentucky. It was believed that the federal government was and should be responsible for covering the costs of the road because it was needed to connect Kentucky to the rest of the eastern seaboard.