1. Gene Therapy for Alzheimer's Disease
... factor gene therapy for Alzheimer disease This journal uses the Nerve Growth Factor (NGF) gene as a means of treating the symptom of cholinergic neuron loss in Alzheimer's disease patients. Basal forebrain Cholinergic neurons are responsible for releasing the majority of acetylcholine in the cerebral cortex and the hippocampus which enhances the ability of presynaptic input to influence the postsynaptic output. Nerve ... as it has been done through pharmaceutical inhibition of ACAT and genetic destruction of ACAT in AD mice and has shown varying degrees of success on improved cognitive...
- Word Count: 5609
- Approx Pages: 22
- Grade Level: Undergraduate